Endocrine Abstracts

Introduction: Angiogenesis is known to play an important role in the development, growth, and metastasis of carcinomas. The vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) are major molecules involved in angiogenesis. The VEGF family includes seven members, respectively named VEGF-A (often simply denoted as VEGF), VEGF-B, VEGF-C, VEGF-D, VEGF-E, VEGF-F, and placental growth factor. The VEGFR is a tyrosine kinase receptor with one to three types and is activ...